The Moog synthesizer, developed by Robert Moog and first sold in 1964, is credited for pioneering analog synthesis concepts such as voltage-controlled oscillators, envelopes, noise generators, filters, and sequencers.
Synthesizer-like instruments emerged in the United States in the mid-20th century with instruments such as the RCA Mark II, which was controlled with punch cards and used hundreds of vacuum tubes. A sample of several common synthesizers (Moog Model D, Juno 106, and TB-303) being played together.